Using all the features on the M-Audio Axiom Pro 61 will definitely take some time as you will need to assign everything to your DAW. Still, once it's all set up the way you like it, it shouldn't be hard to operate everything as it's merely going to be a controller for what you have inside the box. It's built well and definitely sturdier than the standard version of the Axiom 61.
The M-Audio Axiom Pro 61 is a great overall MIDI controller, considering both it's a vast array of features and controls and it's very reasonable price. It really does seem like M-Audio is the king when it comes to MIDI controllers of all shapes, sizes, and price ranges. They've really got something for everyone and in everyone's price range. While the Axiom Pro 61 is definitely one of their more complete controllers, it still doesn't cost a boat load of cash. It has the perfect amount of keys in my opinion, as you can play full two hand parts as well as simpler lead lines with one hand. I also enjoy the feel of the keyboard as although it's not completely weighted, it's the perfect in between as it feels real without being too heavy. If you are looking for a complete MIDI controller at a reasonable price, the M-Audio Axiom Pro 61 (and the standard Axiom 61) are a must see.