We must spend some time playing with all the options. The sound palette is very wide and it takes some time to find happiness - but then it really is bliss!
I play mostly on a Gibson Les Paul Custom, a Gibson Firebird, a Gibson Lucille and a Fender Custom Shop Rory Gallagher. I cover a variety of styles ranging from blues to funk, pop, punk and good old hard rock. I find my happiness with this amp extremely versatile and very typed at a time. I'm not an ayatollah lamps (I also play with a Line 6 Vetta HD ...) but I must confess that the dynamic grain you are absolutely inimitable.
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I've had a little less than a year. I tried head Randall, Marshall, Fender, but they lacked the grain Mesa and versatility. It's expensive - but it is the amp for a lifetime. A little too heavy - but it is a sign of strength. I would do it selected the eyes closed. But happiness ...