AlexFocusrite

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Hi Ian,
Apologies as I've only just seen this. I can see that the
Mesa F50 has both a Mono and Stereo Output so either you can use a TS (Instrument) Cable straight into input 1 on the Clarett or you can use a TRS to dual mono cable into inputs 1 and 2.
Since the send level strength is determined by the Gain and the Master Controls on the amp you will need to experiment with the signal, the safest way to do this would to be to hook this up to one of the Clarett's Mic/Line/Inst (Inputs 1 & 2) and Select a Line Level signal in Focusrite Control (Device Settings Page). I would then adjust the amp accordingly, if you find the signal is far too weak then you can always switch this over to INST. I had a look in the Mesa manual (p. 7) but it doesn't look as though any specific level is specified (http://www.mesaboogie.com/media/User%20Manuals/F-Series.pdf).
If however you wanted to use it in stereo then you would need a TRS to dual mono cable and to plug these into Input 1 & 2 on the Clarett. Again I would start with line and experiement. Regarding the cabling from Guitar > Keeley Compressor >
Mesa Boogie F50 Amp the correct cables to use are regular TS Instrument Cables.
Best regards,
Alex Bull // Focusrite Tech Support
[ Post last edited on 08/16/2017 at 02:45:21 ]