We have the Arturia CS-80V synthesizer running at the studio where I'm working, which has it on a Pro Tools HD based system. It won't usually get used in Pro Tools however, as mostly it's used in Logic on this system. We have a few different studios, but it generally gets used in the smaller productions suites rather than the main room. Either way, all our systems are pretty sturdy and can handle running this software no matter what it's running with.
There's a ton of different sounds that are possible with the Arturia CS-80V, which are valuable to have regardless of if you're looking for sounds like the Yamaha CS-80 or not. I haven't delved into the CS-80V as much as is possible at all, but I've used it enough I think to get a good feel of the different sounds possible here, which are certainly vast. It's definitely got the sound of a 70's into the 80's synthesizer, which is great if you're going for that sort of vibe as I often am. If you're interested in this software at all, it's not too expensive as far as high quality software synths go, so definitely do yourself a favor and check it out.