I'm running the Waves Ltd. CLA Guitars and the Waves Complete bundle on my home recording rig, which is Pro Tools LE based. I'm running everything on a Mac Book Pro that has a 2.2 Ghz Intel Core 2 Duo processor and 4 GB of RAM. Pro Tools LE is running with a Digi 002R audio interface and I'm running version number 8 of the software. This has been a very stable system for me over the last few years, and I can't say that I've had any issues running this plug-in here.
While I don't find myself using the Waves Ltd. CLA Guitars plug-in as much as I do some of the others in the Chris Lord-Alge (CLA) bundle, it's still a very useful plug-in for guitars. It's basically a one stop shop for in the box guitar processing, using high quality effects and overall sounds. All of the sounds on here are pretty realistic, but I'd say that I like using it best as an overall plug-in, not necessarily singling out any one effect here as I believe they work well in tandem rather than separately. If I'm doing a full on mix I'll use outboard gear when possible, but for getting some quick and easy guitar tones, the CLA Guitars plug-in has everything you need.